Hi
The professional part of your wife's nurse practitioner qualification, that is, the prescribing, assessing, diagnosing part won't be recognised here. Nurse practitioners are having a pretty rough ride of it just now- they are having hours cut and jobs are hard to come by. Medics here (on the whole) don't want NPs it's quite political The NPs role here is not as autonomous as UK NPs.
Nirsing here is very (very) different. Patient load smaller, autonomy is very limited- they actually have "doctors orders" lol However, in saying all that... good opportunities for UK nurses and money is better.
Good luck